As demonstrated in our in vivo experiments, the ranges of phosphorylated MEK1/2, ERK1/two, and p90RSK proteins had been augmented by phenylephrine therapy in a timedependent method in mock-transfected cells
Following, we investigated whether or not exogenous TGF-b1 could rescue the inhibitroy results of CARP on the hypertrophic response of cardiomyocytes. Both equally phenylephrine and human TGF-b1 (hTGF-b1, R&D Methods)…