Product Name :
DFP00173
Description:
DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ∼0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9.
CAS:
672286-03-2
Molecular Weight:
332.16
Formula:
C11H7Cl2N3O3S
Chemical Name:
1-(2,6-dichlorophenyl)-3-(5-nitrothiophen-3-yl)urea
Smiles :
[O-][N+](=O)C1=CC(=CS1)NC(=O)NC1C(Cl)=CC=CC=1Cl
InChiKey:
AATXXTHMITUAOJ-UHFFFAOYSA-N
InChi :
InChI=1S/C11H7Cl2N3O3S/c12-7-2-1-3-8(13)10(7)15-11(17)14-6-4-9(16(18)19)20-5-6/h1-5H,(H2,14,15,17)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Brimonidine} medchemexpress|{Brimonidine} Neuronal Signaling|{Brimonidine} Biological Activity|{Brimonidine} Purity|{Brimonidine} manufacturer|{Brimonidine} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ∼0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9.|Product information|CAS Number: 672286-03-2|Molecular Weight: 332.16|Formula: C11H7Cl2N3O3S|Chemical Name: 1-(2,6-dichlorophenyl)-3-(5-nitrothiophen-3-yl)urea|Smiles: [O-][N+](=O)C1=CC(=CS1)NC(=O)NC1C(Cl)=CC=CC=1Cl|InChiKey: AATXXTHMITUAOJ-UHFFFAOYSA-N|InChi: InChI=1S/C11H7Cl2N3O3S/c12-7-2-1-3-8(13)10(7)15-11(17)14-6-4-9(16(18)19)20-5-6/h1-5H,(H2,14,15,17)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (376.{{Tegafur-Uracil} web|{Tegafur-Uracil} Purity & Documentation|{Tegafur-Uracil} In Vitro|{Tegafur-Uracil} custom synthesis|{Tegafur-Uracil} Epigenetic Reader Domain} 32 mM; Need ultrasonic).PMID:34856019 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|DFP00173 inhibits the glycerol permeability of human erythrocytes with an IC50 of ~0.2 µM.|Products are for research use only. Not for human use.|