Product Name :
Nardosinone
Description:
Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances.
CAS:
23720-80-1
Molecular Weight:
250.33
Formula:
C15H22O3
Chemical Name:
(3aR,9R,9aR,9bS)-1,1,9,9a-tetramethyl-1H,3aH,4H,5H,7H,8H,9H,9aH,9bH-naphtho[2,1-c][1,2]dioxol-5-one
Smiles :
CC1(C)OO[C@@H]2CC(=O)C3=CCC[C@@H](C)[C@]3(C)[C@H]12
InChiKey:
KXGHHSIMRWPVQM-JWFUOXDNSA-N
InChi :
InChI=1S/C15H22O3/c1-9-6-5-7-10-11(16)8-12-13(15(9,10)4)14(2,3)18-17-12/h7,9,12-13H,5-6,8H2,1-4H3/t9-,12-,13+,15+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Everolimus} site|{Everolimus} Cell Cycle/DNA Damage|{Everolimus} Technical Information|{Everolimus} Data Sheet|{Everolimus} manufacturer|{Everolimus} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances.|Product information|CAS Number: 23720-80-1|Molecular Weight: 250.33|Formula: C15H22O3|Chemical Name: (3aR,9R,9aR,9bS)-1,1,9,9a-tetramethyl-1H,3aH,4H,5H,7H,8H,9H,9aH,9bH-naphtho[2,1-c][1,2]dioxol-5-one|Smiles: CC1(C)OO[C@@H]2CC(=O)C3=CCC[C@@H](C)[C@]3(C)[C@H]12|InChiKey: KXGHHSIMRWPVQM-JWFUOXDNSA-N|InChi: InChI=1S/C15H22O3/c1-9-6-5-7-10-11(16)8-12-13(15(9,10)4)14(2,3)18-17-12/h7,9,12-13H,5-6,8H2,1-4H3/t9-,12-,13+,15+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (998.{{Bosentan} MedChemExpress|{Bosentan} Endothelin Receptor|{Bosentan} Biological Activity|{Bosentan} In Vivo|{Bosentan} custom synthesis|{Bosentan} Epigenetic Reader Domain} 68 mM; Need ultrasonic).PMID:23746961 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Nardosinone (0.1-100 microM) enhanced dibutyryl cyclic AMP (dbcAMP, 0.3 mM)- and staurosporine (10 nM)-induced neurite outgrowth from PC12D cells in a concentration-dependent manner. Nardosinone enhances a downstream step of MAP kinase in the MAP kinase-dependent signaling pathway.|Products are for research use only. Not for human use.|