Product Name :
Emixustat hydrochloride

Description:
Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. IC50 value: 232 nM Target: 11-cis-retinolEmixustat hydrochloride is a novel visual cycle modulator, in healthy volunteers. Oral Emixustat was safe and well tolerated when administered once daily for 14 days with minimal systemic adverse events reported. Evaluation of emixustat in subjects with geographic atrophy associated with dry age-related macular degeneration.

CAS:
1141934-97-5

Molecular Weight:
299.84

Formula:
C16H26ClNO2

Chemical Name:
(1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol hydrochloride

Smiles :
Cl.NCC[C@@H](O)C1=CC=CC(=C1)OCC1CCCCC1

InChiKey:
BPZWRYOUJMDQSY-PKLMIRHRSA-N

InChi :
InChI=1S/C16H25NO2.ClH/c17-10-9-16(18)14-7-4-8-15(11-14)19-12-13-5-2-1-3-6-13;/h4,7-8,11,13,16,18H,1-3,5-6,9-10,12,17H2;1H/t16-;/m1./s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Olodaterol} medchemexpress|{Olodaterol} Adrenergic Receptor|{Olodaterol} Technical Information|{Olodaterol} Description|{Olodaterol} supplier|{Olodaterol} Cancer}

Additional information:
Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. IC50 value: 232 nM Target: 11-cis-retinolEmixustat hydrochloride is a novel visual cycle modulator, in healthy volunteers. Oral Emixustat was safe and well tolerated when administered once daily for 14 days with minimal systemic adverse events reported. Evaluation of emixustat in subjects with geographic atrophy associated with dry age-related macular degeneration.|Product information|CAS Number: 1141934-97-5|Molecular Weight: 299.84|Formula: C16H26ClNO2|Chemical Name: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol hydrochloride|Smiles: Cl.{{Tazarotene} web|{Tazarotene} Vitamin D Related/Nuclear Receptor|{Tazarotene} Biological Activity|{Tazarotene} In stock|{Tazarotene} custom synthesis|{Tazarotene} Autophagy} NCC[C@@H](O)C1=CC=CC(=C1)OCC1CCCCC1|InChiKey: BPZWRYOUJMDQSY-PKLMIRHRSA-N|InChi: InChI=1S/C16H25NO2.PMID:24456950 ClH/c17-10-9-16(18)14-7-4-8-15(11-14)19-12-13-5-2-1-3-6-13;/h4,7-8,11,13,16,18H,1-3,5-6,9-10,12,17H2;1H/t16-;/m1./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 44 mg/mL (146.74 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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