Product Name :
(Z)-JIB-04
Description:
(Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis.
CAS:
199596-24-2
Molecular Weight:
308.76
Formula:
C17H13ClN4
Chemical Name:
5-chloro-2-[(Z)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine
Smiles :
ClC1=CN=C(C=C1)N/N=C(\C1=CC=CC=N1)/C1C=CC=CC=1
InChiKey:
YHHFKWKMXWRVTJ-XLNRJJMWSA-N
InChi :
InChI=1S/C17H13ClN4/c18-14-9-10-16(20-12-14)21-22-17(13-6-2-1-3-7-13)15-8-4-5-11-19-15/h1-12H,(H,20,21)/b22-17-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
(Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis.|Product information|CAS Number: 199596-24-2|Molecular Weight: 308.76|Formula: C17H13ClN4|Chemical Name: 5-chloro-2-[(Z)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine|Smiles: ClC1=CN=C(C=C1)N/N=C(\C1=CC=CC=N1)/C1C=CC=CC=1|InChiKey: YHHFKWKMXWRVTJ-XLNRJJMWSA-N|InChi: InChI=1S/C17H13ClN4/c18-14-9-10-16(20-12-14)21-22-17(13-6-2-1-3-7-13)15-8-4-5-11-19-15/h1-12H,(H,20,21)/b22-17-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 6 mg/mL (19.{{p-Coumaric acid} site|{p-Coumaric acid} Apoptosis|{p-Coumaric acid} Technical Information|{p-Coumaric acid} Formula|{p-Coumaric acid} supplier|{p-Coumaric acid} Cancer} 43 mM; Need ultrasonic).{{Chenodeoxycholic Acid} web|{Chenodeoxycholic Acid} Autophagy|{Chenodeoxycholic Acid} Purity & Documentation|{Chenodeoxycholic Acid} References|{Chenodeoxycholic Acid} supplier|{Chenodeoxycholic Acid} Epigenetic Reader Domain} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24318587 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|JIB-04 inhibits the demethylase activity of Jumonji enzymes in vitro and in cells, without affecting other α-ketoglutarate dependent hydroxylases or histone modifying enzymes .|Products are for research use only. Not for human use.|