Product Name :
Anti-virus agent 1
Description:
Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV).
CAS:
1911578-83-0
Molecular Weight:
560.50
Formula:
C24H29N6O8P
Chemical Name:
propan-2-yl (2S)-2-[({[(2R,3S,4R,5R)-5-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy}(phenoxy)phosphoryl)amino]propanoate
Smiles :
CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@](C#N)([C@H](O)[C@@H]1O)C1=CC=C2C(N)=NC=NN12)OC1C=CC=CC=1
InChiKey:
QXBLGVOITWEDBZ-XBIBZECMSA-N
InChi :
InChI=1S/C24H29N6O8P/c1-14(2)36-23(33)15(3)29-39(34,38-16-7-5-4-6-8-16)35-11-18-20(31)21(32)24(12-25,37-18)19-10-9-17-22(26)27-13-28-30(17)19/h4-10,13-15,18,20-21,31-32H,11H2,1-3H3,(H,29,34)(H2,26,27,28)/t15-,18+,20+,21+,24-,39?/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Biotin} MedChemExpress|{Biotin} Metabolic Enzyme/Protease|{Biotin} Purity & Documentation|{Biotin} Description|{Biotin} manufacturer|{Biotin} Cancer}
Additional information:
Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity.{{Telisotuzumab vedotin} medchemexpress|{Telisotuzumab vedotin} Protein Tyrosine Kinase/RTK|{Telisotuzumab vedotin} Technical Information|{Telisotuzumab vedotin} Purity|{Telisotuzumab vedotin} custom synthesis|{Telisotuzumab vedotin} Autophagy} Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV).PMID:25558565 |Product information|CAS Number: 1911578-83-0|Molecular Weight: 560.50|Formula: C24H29N6O8P|Chemical Name: propan-2-yl (2S)-2-[({[(2R,3S,4R,5R)-5-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy}(phenoxy)phosphoryl)amino]propanoate|Smiles: CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@](C#N)([C@H](O)[C@@H]1O)C1=CC=C2C(N)=NC=NN12)OC1C=CC=CC=1|InChiKey: QXBLGVOITWEDBZ-XBIBZECMSA-N|InChi: InChI=1S/C24H29N6O8P/c1-14(2)36-23(33)15(3)29-39(34,38-16-7-5-4-6-8-16)35-11-18-20(31)21(32)24(12-25,37-18)19-10-9-17-22(26)27-13-28-30(17)19/h4-10,13-15,18,20-21,31-32H,11H2,1-3H3,(H,29,34)(H2,26,27,28)/t15-,18+,20+,21+,24-,39?/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 200 mg/mL (356.82 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Anti-virus agent 1 (compound 4i) has antiviral activity for EBOV in HeLa cell (EC50=1845 nM), HMVEC cell (TERT-immortalized human foreskin microvascular endothelial cells; ATCC-4025; EC50=367 nM), human macrophages (EC50=297 nM). Anti-virus agent 1 has a CC50 of 21 μM in MT4 cell (human leukemia T-cell).|Products are for research use only. Not for human use.|