Product Name :
Ribociclib D6
Description:
Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.
CAS:
1328934-40-2
Molecular Weight:
440.57
Formula:
C23H30N8O
Chemical Name:
7-cyclopentyl-N,N-di(²H₃)methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
Smiles :
[2H]C([2H])([2H])N(C(=O)C1=CC2=CN=C(NC3=CC=C(C=N3)N3CCNCC3)N=C2N1C1CCCC1)C([2H])([2H])[2H]
InChiKey:
RHXHGRAEPCAFML-WFGJKAKNSA-N
InChi :
InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28)/i1D3,2D3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Prolgolimab} medchemexpress|{Prolgolimab} Immunology/Inflammation|{Prolgolimab} Technical Information|{Prolgolimab} In Vivo|{Prolgolimab} supplier|{Prolgolimab} Epigenetics}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib.{{S2116} web|{S2116} Apoptosis|{S2116} Biological Activity|{S2116} Formula|{S2116} custom synthesis|{S2116} Autophagy} Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.PMID:23903683 |Product information|CAS Number: 1328934-40-2|Molecular Weight: 440.57|Formula: C23H30N8O|Chemical Name: 7-cyclopentyl-N,N-di(²H₃)methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide|Smiles: [2H]C([2H])([2H])N(C(=O)C1=CC2=CN=C(NC3=CC=C(C=N3)N3CCNCC3)N=C2N1C1CCCC1)C([2H])([2H])[2H]|InChiKey: RHXHGRAEPCAFML-WFGJKAKNSA-N|InChi: InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28)/i1D3,2D3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|