Product Name :
Etelcalcetide
Description:
Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.
CAS:
1262780-97-1
Molecular Weight:
1048.25
Formula:
C38H73N21O10S2
Chemical Name:
(2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-carbamoyl-4-[(diaminomethylidene)amino]butyl]carbamoyl}ethyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}ethyl]carbamoyl}-2-acetamidoethyl]disulfanyl}propanoic acid
Smiles :
CC(=O)N[C@H](CSSC[C@H](N)C(O)=O)C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(N)=O
InChiKey:
ANIAZGVDEUQPRI-ZJQCGQFWSA-N
InChi :
InChI=1S/C38H73N21O10S2/c1-18(28(62)56-22(27(40)61)8-4-12-49-35(41)42)53-30(64)23(9-5-13-50-36(43)44)58-32(66)25(11-7-15-52-38(47)48)59-31(65)24(10-6-14-51-37(45)46)57-29(63)19(2)54-33(67)26(55-20(3)60)17-71-70-16-21(39)34(68)69/h18-19,21-26H,4-17,39H2,1-3H3,(H2,40,61)(H,53,64)(H,54,67)(H,55,60)(H,56,62)(H,57,63)(H,58,66)(H,59,65)(H,68,69)(H4,41,42,49)(H4,43,44,50)(H4,45,46,51)(H4,47,48,52)/t18-,19-,21+,22-,23-,24-,25-,26-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Brazikumab} MedChemExpress|{Brazikumab} Interleukin Related|{Brazikumab} Protocol|{Brazikumab} Data Sheet|{Brazikumab} supplier|{Brazikumab} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Sapacitabine} web|{Sapacitabine} Nucleoside Antimetabolite/Analog|{Sapacitabine} Biological Activity|{Sapacitabine} Data Sheet|{Sapacitabine} custom synthesis|{Sapacitabine} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32180353
Additional information:
Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.|Product information|CAS Number: 1262780-97-1|Molecular Weight: 1048.25|Formula: C38H73N21O10S2|Chemical Name: (2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-carbamoyl-4-[(diaminomethylidene)amino]butyl]carbamoyl}ethyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}ethyl]carbamoyl}-2-acetamidoethyl]disulfanyl}propanoic acid|Smiles: CC(=O)N[C@H](CSSC[C@H](N)C(O)=O)C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(N)=O|InChiKey: ANIAZGVDEUQPRI-ZJQCGQFWSA-N|InChi: InChI=1S/C38H73N21O10S2/c1-18(28(62)56-22(27(40)61)8-4-12-49-35(41)42)53-30(64)23(9-5-13-50-36(43)44)58-32(66)25(11-7-15-52-38(47)48)59-31(65)24(10-6-14-51-37(45)46)57-29(63)19(2)54-33(67)26(55-20(3)60)17-71-70-16-21(39)34(68)69/h18-19,21-26H,4-17,39H2,1-3H3,(H2,40,61)(H,53,64)(H,54,67)(H,55,60)(H,56,62)(H,57,63)(H,58,66)(H,59,65)(H,68,69)(H4,41,42,49)(H4,43,44,50)(H4,45,46,51)(H4,47,48,52)/t18-,19-,21+,22-,23-,24-,25-,26-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|