Product Name :
Etelcalcetide hydrochloride
Description:
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.
CAS:
1334237-71-6
Molecular Weight:
1084.71
Formula:
C38H74ClN21O10S2
Chemical Name:
(2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-carbamoyl-4-[(diaminomethylidene)amino]butyl]carbamoyl}ethyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}ethyl]carbamoyl}-2-acetamidoethyl]disulfanyl}propanoic acid hydrochloride
Smiles :
Cl.CC(=O)N[C@H](CSSC[C@H](N)C(O)=O)C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(N)=O
InChiKey:
KHQMSZGKHGQUHG-WZDHWKSBSA-N
InChi :
InChI=1S/C38H73N21O10S2.ClH/c1-18(28(62)56-22(27(40)61)8-4-12-49-35(41)42)53-30(64)23(9-5-13-50-36(43)44)58-32(66)25(11-7-15-52-38(47)48)59-31(65)24(10-6-14-51-37(45)46)57-29(63)19(2)54-33(67)26(55-20(3)60)17-71-70-16-21(39)34(68)69;/h18-19,21-26H,4-17,39H2,1-3H3,(H2,40,61)(H,53,64)(H,54,67)(H,55,60)(H,56,62)(H,57,63)(H,58,66)(H,59,65)(H,68,69)(H4,41,42,49)(H4,43,44,50)(H4,45,46,51)(H4,47,48,52);1H/t18-,19-,21+,22-,23-,24-,25-,26-;/m1./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.|Product information|CAS Number: 1334237-71-6|Molecular Weight: 1084.71|Formula: C38H74ClN21O10S2|Chemical Name: (2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-carbamoyl-4-[(diaminomethylidene)amino]butyl]carbamoyl}ethyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}ethyl]carbamoyl}-2-acetamidoethyl]disulfanyl}propanoic acid hydrochloride|Smiles: Cl.CC(=O)N[C@H](CSSC[C@H](N)C(O)=O)C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(N)=O|InChiKey: KHQMSZGKHGQUHG-WZDHWKSBSA-N|InChi: InChI=1S/C38H73N21O10S2.ClH/c1-18(28(62)56-22(27(40)61)8-4-12-49-35(41)42)53-30(64)23(9-5-13-50-36(43)44)58-32(66)25(11-7-15-52-38(47)48)59-31(65)24(10-6-14-51-37(45)46)57-29(63)19(2)54-33(67)26(55-20(3)60)17-71-70-16-21(39)34(68)69;/h18-19,21-26H,4-17,39H2,1-3H3,(H2,40,61)(H,53,64)(H,54,67)(H,55,60)(H,56,62)(H,57,63)(H,58,66)(H,59,65)(H,68,69)(H4,41,42,49)(H4,43,44,50)(H4,45,46,51)(H4,47,48,52);1H/t18-,19-,21+,22-,23-,24-,25-,26-;/m1.{{Boceprevir} MedChemExpress|{Boceprevir} HCV|{Boceprevir} Purity & Documentation|{Boceprevir} In Vivo|{Boceprevir} supplier|{Boceprevir} Cancer} /s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : ≥ 50 mg/mL (36.{{SNPB} medchemexpress|{SNPB} ADC Linker|{SNPB} Biological Activity|{SNPB} Data Sheet|{SNPB} manufacturer|{SNPB} Autophagy} 95 mM).PMID:24189672 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|