Product Name :
AZ084

Description:
AZ084 is a potent, selective, allosteric and oral active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma.

CAS:
929300-19-6

Molecular Weight:
434.57

Formula:
C26H34N4O2

Chemical Name:
6-{9-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-4-yl)methyl]-3,9-diazaspiro[5.5]undecane-3-carbonyl}pyridin-3-amine

Smiles :
CC1(C)CC2=C(C=CC=C2CN2CCC3(CCN(CC3)C(=O)C3=CC=C(N)C=N3)CC2)O1

InChiKey:
WIGFMKMFRGRSDE-UHFFFAOYSA-N

InChi :
InChI=1S/C26H34N4O2/c1-25(2)16-21-19(4-3-5-23(21)32-25)18-29-12-8-26(9-13-29)10-14-30(15-11-26)24(31)22-7-6-20(27)17-28-22/h3-7,17H,8-16,18,27H2,1-2H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
AZ084 is a potent, selective, allosteric and oral active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma.|Product information|CAS Number: 929300-19-6|Molecular Weight: 434.57|Formula: C26H34N4O2|Chemical Name: 6-{9-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-4-yl)methyl]-3,9-diazaspiro[5.5]undecane-3-carbonyl}pyridin-3-amine|Smiles: CC1(C)CC2=C(C=CC=C2CN2CCC3(CCN(CC3)C(=O)C3=CC=C(N)C=N3)CC2)O1|InChiKey: WIGFMKMFRGRSDE-UHFFFAOYSA-N|InChi: InChI=1S/C26H34N4O2/c1-25(2)16-21-19(4-3-5-23(21)32-25)18-29-12-8-26(9-13-29)10-14-30(15-11-26)24(31)22-7-6-20(27)17-28-22/h3-7,17H,8-16,18,27H2,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (575.{{GDNF Protein, Human} MedChemExpress|{GDNF Protein, Human} Technical Information|{GDNF Protein, Human} In Vivo|{GDNF Protein, Human} custom synthesis|{GDNF Protein, Human} Epigenetic Reader Domain} 28 mM; Need ultrasonic).{{Mirvetuximab} MedChemExpress|{Mirvetuximab} Cell Cycle/DNA Damage|{Mirvetuximab} Protocol|{Mirvetuximab} In Vitro|{Mirvetuximab} manufacturer|{Mirvetuximab} Autophagy} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23996047 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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