Product Name :
ML604086
Description:
ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations.
CAS:
850330-18-6
Molecular Weight:
508.63
Formula:
C27H32N4O4S
Chemical Name:
N-(4-{[(3R,4R)-1-[(2S)-2-aminopropanoyl]-3-methylpiperidin-4-yl]sulfamoyl}naphthalen-1-yl)-2-methylbenzamide
Smiles :
CC1=CC=CC=C1C(=O)NC1=CC=C(C2=CC=CC=C12)S(=O)(=O)N[C@@H]1CCN(C[C@H]1C)C(=O)[C@H](C)N
InChiKey:
FABRBEGQMXBELT-SELNLUPBSA-N
InChi :
InChI=1S/C27H32N4O4S/c1-17-8-4-5-9-20(17)26(32)29-24-12-13-25(22-11-7-6-10-21(22)24)36(34,35)30-23-14-15-31(16-18(23)2)27(33)19(3)28/h4-13,18-19,23,30H,14-16,28H2,1-3H3,(H,29,32)/t18-,19+,23-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{DPPE-mPEG} medchemexpress|{DPPE-mPEG} Metabolic Enzyme/Protease|{DPPE-mPEG} Technical Information|{DPPE-mPEG} In Vitro|{DPPE-mPEG} custom synthesis|{DPPE-mPEG} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Ofatumumab} medchemexpress|{Ofatumumab} Immunology/Inflammation|{Ofatumumab} Technical Information|{Ofatumumab} References|{Ofatumumab} supplier|{Ofatumumab} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:35954127
Additional information:
ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations.|Product information|CAS Number: 850330-18-6|Molecular Weight: 508.63|Formula: C27H32N4O4S|Chemical Name: N-(4-{[(3R,4R)-1-[(2S)-2-aminopropanoyl]-3-methylpiperidin-4-yl]sulfamoyl}naphthalen-1-yl)-2-methylbenzamide|Smiles: CC1=CC=CC=C1C(=O)NC1=CC=C(C2=CC=CC=C12)S(=O)(=O)N[C@@H]1CCN(C[C@H]1C)C(=O)[C@H](C)N|InChiKey: FABRBEGQMXBELT-SELNLUPBSA-N|InChi: InChI=1S/C27H32N4O4S/c1-17-8-4-5-9-20(17)26(32)29-24-12-13-25(22-11-7-6-10-21(22)24)36(34,35)30-23-14-15-31(16-18(23)2)27(33)19(3)28/h4-13,18-19,23,30H,14-16,28H2,1-3H3,(H,29,32)/t18-,19+,23-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 120 mg/mL (235.93 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|