Product Name :
Fmoc-NH-PEG1-CH2COOH
Description:
Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG1-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
260367-12-2
Molecular Weight:
341.36
Formula:
C19H19NO5
Chemical Name:
2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]acetic acid
Smiles :
OC(=O)COCCNC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21
InChiKey:
LBVXPUINIMIGAU-UHFFFAOYSA-N
InChi :
InChI=1S/C19H19NO5/c21-18(22)12-24-10-9-20-19(23)25-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17H,9-12H2,(H,20,23)(H,21,22)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG1-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 260367-12-2|Molecular Weight: 341.36|Formula: C19H19NO5|Chemical Name: 2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]acetic acid|Smiles: OC(=O)COCCNC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21|InChiKey: LBVXPUINIMIGAU-UHFFFAOYSA-N|InChi: InChI=1S/C19H19NO5/c21-18(22)12-24-10-9-20-19(23)25-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17H,9-12H2,(H,20,23)(H,21,22)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tween 80} medchemexpress|{Tween 80} {Biochemical Assay Reagents}|{Tween 80} Biological Activity|{Tween 80} In Vivo|{Tween 80} custom synthesis|{Tween 80} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Bisphenol A} site|{Bisphenol A} Endogenous Metabolite|{Bisphenol A} Biological Activity|{Bisphenol A} In stock|{Bisphenol A} custom synthesis|{Bisphenol A} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23514335 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|