Product Name :
VP3.15 dihydrobromide
Description:
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS).
CAS:
1281681-33-1
Molecular Weight:
528.30
Formula:
C20H24Br2N4OS
Chemical Name:
N-(2,3-diphenyl-2,5-dihydro-1,2,4-thiadiazol-5-ylidene)-2-(morpholin-4-yl)ethan-1-amine dihydrobromide
Smiles :
Br.Br.C(CN=C1N=C(C2C=CC=CC=2)N(S1)C1C=CC=CC=1)N1CCOCC1
InChiKey:
CAJZOXQDSKOPBU-SERMZQFOSA-N
InChi :
InChI=1S/C20H22N4OS.2BrH/c1-3-7-17(8-4-1)19-22-20(21-11-12-23-13-15-25-16-14-23)26-24(19)18-9-5-2-6-10-18;;/h1-10H,11-16H2;2*1H/b21-20+;;
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS).{{Nomegestrol} web|{Nomegestrol} Progesterone Receptor|{Nomegestrol} Protocol|{Nomegestrol} In stock|{Nomegestrol} supplier|{Nomegestrol} Epigenetic Reader Domain} |Product information|CAS Number: 1281681-33-1|Molecular Weight: 528.{{Tolfenamic Acid} MedChemExpress|{Tolfenamic Acid} Immunology/Inflammation|{Tolfenamic Acid} Protocol|{Tolfenamic Acid} Data Sheet|{Tolfenamic Acid} supplier|{Tolfenamic Acid} Cancer} 30|Formula: C20H24Br2N4OS|Chemical Name: N-(2,3-diphenyl-2,5-dihydro-1,2,4-thiadiazol-5-ylidene)-2-(morpholin-4-yl)ethan-1-amine dihydrobromide|Smiles: Br.PMID:24293312 Br.C(CN=C1N=C(C2C=CC=CC=2)N(S1)C1C=CC=CC=1)N1CCOCC1|InChiKey: CAJZOXQDSKOPBU-SERMZQFOSA-N|InChi: InChI=1S/C20H22N4OS.2BrH/c1-3-7-17(8-4-1)19-22-20(21-11-12-23-13-15-25-16-14-23)26-24(19)18-9-5-2-6-10-18;;/h1-10H,11-16H2;2*1H/b21-20+;;|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 62.5 mg/mL (118.30 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|