Product Name :
Bromo-PEG2-C2-azide
Description:
Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bromo-PEG2-C2-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
530151-56-5
Molecular Weight:
238.08
Formula:
C6H12BrN3O2
Chemical Name:
1-azido-2-[2-(2-bromoethoxy)ethoxy]ethane
Smiles :
[N-]=[N+]=NCCOCCOCCBr
InChiKey:
QZCKRLVDTQCBFT-UHFFFAOYSA-N
InChi :
InChI=1S/C6H12BrN3O2/c7-1-3-11-5-6-12-4-2-9-10-8/h1-6H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bromo-PEG2-C2-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 530151-56-5|Molecular Weight: 238.08|Formula: C6H12BrN3O2|Chemical Name: 1-azido-2-[2-(2-bromoethoxy)ethoxy]ethane|Smiles: [N-]=[N+]=NCCOCCOCCBr|InChiKey: QZCKRLVDTQCBFT-UHFFFAOYSA-N|InChi: InChI=1S/C6H12BrN3O2/c7-1-3-11-5-6-12-4-2-9-10-8/h1-6H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Netarsudil} web|{Netarsudil} TGF-beta/Smad|{Netarsudil} Protocol|{Netarsudil} Formula|{Netarsudil} supplier|{Netarsudil} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Ambrisentan} MedChemExpress|{Ambrisentan} Endothelin Receptor|{Ambrisentan} Biological Activity|{Ambrisentan} Data Sheet|{Ambrisentan} supplier|{Ambrisentan} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:28630660 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|