Product Name :
NH-bis-PEG2
Description:
NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH-bis-PEG2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
54384-47-3
Molecular Weight:
193.24
Formula:
C8H19NO4
Chemical Name:
2-(2-{[2-(2-hydroxyethoxy)ethyl]amino}ethoxy)ethan-1-ol
Smiles :
OCCOCCNCCOCCO
InChiKey:
HPYJVTFKENYYFK-UHFFFAOYSA-N
InChi :
InChI=1S/C8H19NO4/c10-3-7-12-5-1-9-2-6-13-8-4-11/h9-11H,1-8H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH-bis-PEG2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 54384-47-3|Molecular Weight: 193.24|Formula: C8H19NO4|Chemical Name: 2-(2-{[2-(2-hydroxyethoxy)ethyl]amino}ethoxy)ethan-1-ol|Smiles: OCCOCCNCCOCCO|InChiKey: HPYJVTFKENYYFK-UHFFFAOYSA-N|InChi: InChI=1S/C8H19NO4/c10-3-7-12-5-1-9-2-6-13-8-4-11/h9-11H,1-8H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Neflamapimod} site|{Neflamapimod} Autophagy|{Neflamapimod} Biological Activity|{Neflamapimod} Description|{Neflamapimod} manufacturer|{Neflamapimod} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Rotenone} site|{Rotenone} Mitochondrial Metabolism|{Rotenone} Purity & Documentation|{Rotenone} Purity|{Rotenone} manufacturer|{Rotenone} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24624203 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|