Product Name :
Bis-(m-PEG4)-amidohexanoic acid
Description:
Bis-(m-PEG4)-amidohexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2353409-74-0
Molecular Weight:
582.68
Formula:
C26H50N2O12
Chemical Name:
(2R)-2,6-bis(2,5,8,11-tetraoxatetradecan-14-amido)hexanoic acid
Smiles :
COCCOCCOCCOCCC(=O)NCCCC[C@@H](NC(=O)CCOCCOCCOCCOC)C(O)=O
InChiKey:
VEMVVACPIWNZPA-HSZRJFAPSA-N
InChi :
InChI=1S/C26H50N2O12/c1-33-11-13-37-19-21-39-17-15-35-9-6-24(29)27-8-4-3-5-23(26(31)32)28-25(30)7-10-36-16-18-40-22-20-38-14-12-34-2/h23H,3-22H2,1-2H3,(H,27,29)(H,28,30)(H,31,32)/t23-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Givinostat} medchemexpress|{Givinostat} Epigenetics|{Givinostat} Protocol|{Givinostat} References|{Givinostat} custom synthesis|{Givinostat} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Ribociclib} web|{Ribociclib} CDK|{Ribociclib} Biological Activity|{Ribociclib} References|{Ribociclib} supplier|{Ribociclib} Epigenetics}
Additional information:
Bis-(m-PEG4)-amidohexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 2353409-74-0|Molecular Weight: 582.68|Formula: C26H50N2O12|Chemical Name: (2R)-2,6-bis(2,5,8,11-tetraoxatetradecan-14-amido)hexanoic acid|Smiles: COCCOCCOCCOCCC(=O)NCCCC[C@@H](NC(=O)CCOCCOCCOCCOC)C(O)=O|InChiKey: VEMVVACPIWNZPA-HSZRJFAPSA-N|InChi: InChI=1S/C26H50N2O12/c1-33-11-13-37-19-21-39-17-15-35-9-6-24(29)27-8-4-3-5-23(26(31)32)28-25(30)7-10-36-16-18-40-22-20-38-14-12-34-2/h23H,3-22H2,1-2H3,(H,27,29)(H,28,30)(H,31,32)/t23-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23577779 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|