Valnivudine
Product Name : ValnivudineDescription:Valnivudine (FV-100 free base), a prodrug of CF-1743, is an orally active anti-herpes zoster (HZ) nucleoside analogue. CF-1743, a bicyclic nucleoside analog (BCNA), has highly specific antiviral…
NB-360
Product Name : NB-360Description:NB-360 is a potent, brain penetrable, and orally bioavailable dual BACE1/BACE2 inhibitor (IC50: mouse and human BACE1=5 nM; BACE2=6 nM). NB-360 shows a superior pharmacological profile and…
DBCO-PEG4-alcohol
Product Name : DBCO-PEG4-alcoholDescription:DBCO-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 1416711-60-8Molecular Weight:508.61Formula: C29H36N2O6Chemical Name: 6-{2-azatricyclohexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-N-(2-{2-ethoxy}ethyl)-6-oxohexanamideSmiles : OCCOCCOCCOCCNC(=O)CCCCC(=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12InChiKey: ZZXWONCQAFVJHM-UHFFFAOYSA-NInChi : InChI=1S/C29H36N2O6/c32-16-18-36-20-22-37-21-19-35-17-15-30-28(33)11-5-6-12-29(34)31-23-26-9-2-1-7-24(26)13-14-25-8-3-4-10-27(25)31/h1-4,7-10,32H,5-6,11-12,15-23H2,(H,30,33)Purity: ≥98% (or…
MBC-11 triethylamine
Product Name : MBC-11 triethylamineDescription:MBC-11 triethylamine is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC). MBC-11 triethylamine has the potential for tumor-induced bone…
Fluo-3AM
Product Name : Fluo-3AMDescription:Fluo-3AM(Fluo-3-pentaacetoxymethyl ester) is a calcium indicator that exhibit an increase in fluorescence upon binding Ca2+; used to image the spatial dynamics of Ca2+ signaling, in flow cytometry…
Heptaethylene glycol
Product Name : Heptaethylene glycolDescription:Heptaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 5617-32-3Molecular Weight:326.38Formula: C14H30O8Chemical Name: 3,6,9,12,15,18-hexaoxaicosane-1,20-diolSmiles : OCCOCCOCCOCCOCCOCCOCCOInChiKey: XPJRQAIZZQMSCM-UHFFFAOYSA-NInChi : InChI=1S/C14H30O8/c15-1-3-17-5-7-19-9-11-21-13-14-22-12-10-20-8-6-18-4-2-16/h15-16H,1-14H2Purity:…
Bromo-PEG2-NHS ester
Product Name : Bromo-PEG2-NHS esterDescription:Bromo-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 2148295-96-7Molecular Weight:338.15Formula: C11H16BrNO6Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-propanoateSmiles : O=C(CCOCCOCCBr)ON1C(=O)CCC1=OInChiKey: YPQCMIBMAMVCHR-UHFFFAOYSA-NInChi :…
PF-9366
Product Name : PF-9366Description:PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor, with an IC50 of 420 nM and a Kd of 170 nM.CAS: 72882-78-1Molecular Weight:350.84Formula: C20H19ClN4Chemical Name: (2-{7-chloro-5-phenyl-triazoloquinolin-1-yl}ethyl)dimethylamineSmiles :…
Raltegravir (MK-0518)
Product Name : Raltegravir (MK-0518)Description:Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection.CAS: 518048-05-0Molecular Weight:444.42Formula: C20H21FN6O5Chemical Name: N--5-hydroxy-1-methyl-2-{2-propan-2-yl}-6-oxo-1, 6-dihydropyrimidine-4-carboxamideSmiles : CC1=NN=C(O1)C(=O)NC(C)(C)C1=NC(=C(O)C(=O)N1C)C(=O)NCC1C=CC(F)=CC=1InChiKey: CZFFBEXEKNGXKS-UHFFFAOYSA-NInChi : InChI=1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30)Purity: ≥98% (or refer…
DBCO-PEG9-amine
Product Name : DBCO-PEG9-amineDescription:DBCO-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 2353409-99-9Molecular Weight:743.88Formula: C39H57N3O11Chemical Name: N-(29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-yl)-4-{2-azatricyclohexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-4-oxobutanamideSmiles : NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCC(=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12InChiKey: ONUWAJBCFPYIFM-UHFFFAOYSA-NInChi : InChI=1S/C39H57N3O11/c40-13-15-45-17-19-47-21-23-49-25-27-51-29-31-53-32-30-52-28-26-50-24-22-48-20-18-46-16-14-41-38(43)11-12-39(44)42-33-36-7-2-1-5-34(36)9-10-35-6-3-4-8-37(35)42/h1-8H,11-33,40H2,(H,41,43)Purity: ≥98% (or…