Product Name :
Fmoc-NH-PEG5-CH2COOH
Description:
Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
635287-26-2
Molecular Weight:
517.57
Formula:
C27H35NO9
Chemical Name:
17-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,6,9,12,15-pentaoxaheptadecanoic acid
Smiles :
OC(=O)COCCOCCOCCOCCOCCNC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21
InChiKey:
LNIFRTLAPAPKAG-UHFFFAOYSA-N
InChi :
InChI=1S/C27H35NO9/c29-26(30)20-36-18-17-35-16-15-34-14-13-33-12-11-32-10-9-28-27(31)37-19-25-23-7-3-1-5-21(23)22-6-2-4-8-24(22)25/h1-8,25H,9-20H2,(H,28,31)(H,29,30)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Dodecyltrimethylammonium} medchemexpress|{Dodecyltrimethylammonium} {Biochemical Assay Reagents}|{Dodecyltrimethylammonium} Technical Information|{Dodecyltrimethylammonium} In stock|{Dodecyltrimethylammonium} custom synthesis|{Dodecyltrimethylammonium} Autophagy}
Additional information:
Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).{{Carbendazim} site|{Carbendazim} Anti-infection|{Carbendazim} Purity & Documentation|{Carbendazim} In stock|{Carbendazim} custom synthesis|{Carbendazim} Epigenetic Reader Domain} Fmoc-NH-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.PMID:25269910 |Product information|CAS Number: 635287-26-2|Molecular Weight: 517.57|Formula: C27H35NO9|Chemical Name: 17-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,6,9,12,15-pentaoxaheptadecanoic acid|Smiles: OC(=O)COCCOCCOCCOCCOCCNC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21|InChiKey: LNIFRTLAPAPKAG-UHFFFAOYSA-N|InChi: InChI=1S/C27H35NO9/c29-26(30)20-36-18-17-35-16-15-34-14-13-33-12-11-32-10-9-28-27(31)37-19-25-23-7-3-1-5-21(23)22-6-2-4-8-24(22)25/h1-8,25H,9-20H2,(H,28,31)(H,29,30)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|