Product Name :
1, 3-bis(carboxyethoxy)-2, 2-bis(carboxyethoxy)propane
Description:
1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
35638-19-8
Molecular Weight:
424.40
Formula:
C17H28O12
Chemical Name:
3-[3-(2-carboxyethoxy)-2,2-bis[(2-carboxyethoxy)methyl]propoxy]propanoic acid
Smiles :
OC(=O)CCOCC(COCCC(O)=O)(COCCC(O)=O)COCCC(O)=O
InChiKey:
KIGSIPUDIPIMRD-UHFFFAOYSA-N
InChi :
InChI=1S/C17H28O12/c18-13(19)1-5-26-9-17(10-27-6-2-14(20)21,11-28-7-3-15(22)23)12-29-8-4-16(24)25/h1-12H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{K67} medchemexpress|{K67} p62|{K67} Protocol|{K67} Purity|{K67} custom synthesis|{K67} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Ramipril} site|{Ramipril} Apoptosis|{Ramipril} Technical Information|{Ramipril} Formula|{Ramipril} custom synthesis|{Ramipril} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 35638-19-8|Molecular Weight: 424.40|Formula: C17H28O12|Chemical Name: 3-[3-(2-carboxyethoxy)-2,2-bis[(2-carboxyethoxy)methyl]propoxy]propanoic acid|Smiles: OC(=O)CCOCC(COCCC(O)=O)(COCCC(O)=O)COCCC(O)=O|InChiKey: KIGSIPUDIPIMRD-UHFFFAOYSA-N|InChi: InChI=1S/C17H28O12/c18-13(19)1-5-26-9-17(10-27-6-2-14(20)21,11-28-7-3-15(22)23)12-29-8-4-16(24)25/h1-12H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:25105126 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|