Product Name :
Thiol-PEG8-acid
Description:
Thiol-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
866889-02-3
Molecular Weight:
458.56
Formula:
C19H38O10S
Chemical Name:
1-sulfanyl-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid
Smiles :
OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCS
InChiKey:
SKYJRDAORYSCAL-UHFFFAOYSA-N
InChi :
InChI=1S/C19H38O10S/c20-19(21)1-2-22-3-4-23-5-6-24-7-8-25-9-10-26-11-12-27-13-14-28-15-16-29-17-18-30/h30H,1-18H2,(H,20,21)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Briquilimab} MedChemExpress|{Briquilimab} Biological Activity|{Briquilimab} In stock|{Briquilimab} manufacturer|{Briquilimab} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Belimumab} MedChemExpress|{Belimumab} Apoptosis|{Belimumab} Purity & Documentation|{Belimumab} Data Sheet|{Belimumab} custom synthesis|{Belimumab} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:27217159
Additional information:
Thiol-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 866889-02-3|Molecular Weight: 458.56|Formula: C19H38O10S|Chemical Name: 1-sulfanyl-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid|Smiles: OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCS|InChiKey: SKYJRDAORYSCAL-UHFFFAOYSA-N|InChi: InChI=1S/C19H38O10S/c20-19(21)1-2-22-3-4-23-5-6-24-7-8-25-9-10-26-11-12-27-13-14-28-15-16-29-17-18-30/h30H,1-18H2,(H,20,21)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|