Product Name :
Azido-PEG8-acid
Description:
Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
1214319-92-2
Molecular Weight:
467.51
Formula:
C19H37N3O10
Chemical Name:
1-azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid
Smiles :
[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
InChiKey:
URUGOEBULOZLBF-UHFFFAOYSA-N
InChi :
InChI=1S/C19H37N3O10/c20-22-21-2-4-26-6-8-28-10-12-30-14-16-32-18-17-31-15-13-29-11-9-27-7-5-25-3-1-19(23)24/h1-18H2,(H,23,24)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{MK-6240} MedChemExpress|{MK-6240} Purity & Documentation|{MK-6240} Description|{MK-6240} supplier|{MK-6240} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Ulipristal} web|{Ulipristal} Progesterone Receptor|{Ulipristal} Biological Activity|{Ulipristal} In Vitro|{Ulipristal} custom synthesis|{Ulipristal} Epigenetics}
Additional information:
Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1214319-92-2|Molecular Weight: 467.51|Formula: C19H37N3O10|Chemical Name: 1-azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid|Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O|InChiKey: URUGOEBULOZLBF-UHFFFAOYSA-N|InChi: InChI=1S/C19H37N3O10/c20-22-21-2-4-26-6-8-28-10-12-30-14-16-32-18-17-31-15-13-29-11-9-27-7-5-25-3-1-19(23)24/h1-18H2,(H,23,24)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24013184 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|