Product Name :
Agitoxin-2
Description:
Agitoxin-2 is a K+ channel inhibitor, with IC50 values of 201 pM and 144 pM for mKV1.3 and mKV1.1, respectively).
CAS:
168147-41-9
Molecular Weight:
4090.87
Formula:
C169H278N54O48S8
Chemical Name:
6-amino-2-{[1-(3-hydroxy-2-{[15,39,75,92-tetrakis(4-aminobutyl)-47-[2-(2-{2-[2-({1-[2-(2-aminoacetamido)-3-methylbutanoyl]pyrrolidin-2-yl}formamido)-3-methylpentanamido]-3-carbamoylpropanamido}-3-methylbutanamido)-3-hydroxypropanamido]-33-benzyl-89-(butan-2-yl)-30,78-bis(3-carbamimidamidopropyl)-65-(2-carbamoylethyl)-81-(carbamoylmethyl)-18-(carboxymethyl)-50-(1-hydroxyethyl)-56-(hydroxymethyl)-4-[(1H-imidazol-4-yl)methyl]-21-methyl-27,84-bis[2-(methylsulfanyl)ethyl]-2,5,13,16,19,22,25,28,31,34,37,40,48,51,54,57,63,66,74,77,80,83,86,87,90,93,99-heptacosaoxo-9,10,44,45,70,71-hexathia-3,6,14,17,20,23,26,29,32,35,38,41,49,52,55,58,64,67,73,76,79,82,85,88,91,94,100-heptacosaazapentacyclo[40.30.14.14¹²,⁶⁸.0⁵⁸,⁶².0⁹⁴,⁹⁸]100n-7-yl]formamido}butanoyl)pyrrolidin-2-yl]formamido}hexanoic acid
Smiles :
CC(O)C(NC(=O)C1CSSCC2NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C(NC(=O)C3CSSCC(NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(N)=O)NC(=O)C(CCSC)NC(=O)C(CSSCC(NC(=O)C(CO)NC(=O)C(NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C4CCCN4C(=O)C(NC(=O)CN)C(C)C)C(C)CC)C(C)C)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)N4CCCC4C(=O)NC(CCC(N)=O)C(=O)N3)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC3C=CC=CC=3)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCSC)NC(=O)CNC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CCCCN)NC2=O)C(=O)NC(CC2=CNC=N2)C(=O)N1)C(C)CC)C(=O)N1CCCC1C(=O)NC(CCCCN)C(O)=O
InChiKey:
MNSSWZUIQUJZTG-UHFFFAOYSA-N
InChi :
InChI=1S/C169H278N54O48S8/c1-14-86(7)130-161(264)200-101(40-22-27-55-173)163(266)220-59-31-45-117(220)157(260)213-112-79-276-279-82-115(154(257)219-133(90(11)227)166(269)223-62-33-46-118(223)156(259)201-102(167(270)271)41-23-28-56-174)211-145(248)104(66-92-71-183-83-189-92)203-151(254)111-78-275-277-80-113(152(255)216-130)210-141(244)98(48-49-120(176)228)199-155(258)116-44-32-60-221(116)164(267)109(76-225)193-126(234)74-188-159(262)132(89(10)226)218-153(256)114(212-148(251)108(75-224)207-160(263)128(84(3)4)215-147(250)106(68-122(178)230)206-162(265)131(87(8)15-2)217-158(261)119-47-34-61-222(119)165(268)129(85(5)6)214-123(231)70-175)81-278-274-77-110(149(252)198-100(51-64-273-13)143(246)204-105(67-121(177)229)146(249)196-96(42-29-57-184-168(179)180)137(240)194-95(140(243)209-111)39-21-26-54-172)208-136(239)93(37-19-24-52-170)191-125(233)73-187-135(238)103(65-91-35-17-16-18-36-91)202-139(242)97(43-30-58-185-169(181)182)195-142(245)99(50-63-272-12)192-124(232)72-186-134(237)88(9)190-144(247)107(69-127(235)236)205-138(241)94(197-150(112)253)38-20-25-53-171/h16-18,35-36,71,83-90,93-119,128-133,224-227H,14-15,19-34,37-70,72-82,170-175H2,1-13H3,(H2,176,228)(H2,177,229)(H2,178,230)(H,183,189)(H,186,237)(H,187,238)(H,188,262)(H,190,247)(H,191,233)(H,192,232)(H,193,234)(H,194,240)(H,195,245)(H,196,249)(H,197,253)(H,198,252)(H,199,258)(H,200,264)(H,201,259)(H,202,242)(H,203,254)(H,204,246)(H,205,241)(H,206,265)(H,207,263)(H,208,239)(H,209,243)(H,210,244)(H,211,248)(H,212,251)(H,213,260)(H,214,231)(H,215,250)(H,216,255)(H,217,261)(H,218,256)(H,219,257)(H,235,236)(H,270,271)(H4,179,180,184)(H4,181,182,185)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Hesperidin} MedChemExpress|{Hesperidin} Endogenous Metabolite|{Hesperidin} Purity & Documentation|{Hesperidin} Formula|{Hesperidin} custom synthesis|{Hesperidin} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Agitoxin-2 is a K+ channel inhibitor, with IC50 values of 201 pM and 144 pM for mKV1.3 and mKV1.1, respectively).|Product information|CAS Number: 168147-41-9|Molecular Weight: 4090.87|Formula: C169H278N54O48S8|Chemical Name: 6-amino-2-{[1-(3-hydroxy-2-{[15,39,75,92-tetrakis(4-aminobutyl)-47-[2-(2-{2-[2-({1-[2-(2-aminoacetamido)-3-methylbutanoyl]pyrrolidin-2-yl}formamido)-3-methylpentanamido]-3-carbamoylpropanamido}-3-methylbutanamido)-3-hydroxypropanamido]-33-benzyl-89-(butan-2-yl)-30,78-bis(3-carbamimidamidopropyl)-65-(2-carbamoylethyl)-81-(carbamoylmethyl)-18-(carboxymethyl)-50-(1-hydroxyethyl)-56-(hydroxymethyl)-4-[(1H-imidazol-4-yl)methyl]-21-methyl-27,84-bis[2-(methylsulfanyl)ethyl]-2,5,13,16,19,22,25,28,31,34,37,40,48,51,54,57,63,66,74,77,80,83,86,87,90,93,99-heptacosaoxo-9,10,44,45,70,71-hexathia-3,6,14,17,20,23,26,29,32,35,38,41,49,52,55,58,64,67,73,76,79,82,85,88,91,94,100-heptacosaazapentacyclo[40.30.14.14¹²,⁶⁸.0⁵⁸,⁶².0⁹⁴,⁹⁸]100n-7-yl]formamido}butanoyl)pyrrolidin-2-yl]formamido}hexanoic acid|Smiles: CC(O)C(NC(=O)C1CSSCC2NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C(NC(=O)C3CSSCC(NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(N)=O)NC(=O)C(CCSC)NC(=O)C(CSSCC(NC(=O)C(CO)NC(=O)C(NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C4CCCN4C(=O)C(NC(=O)CN)C(C)C)C(C)CC)C(C)C)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)N4CCCC4C(=O)NC(CCC(N)=O)C(=O)N3)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC3C=CC=CC=3)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCSC)NC(=O)CNC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CCCCN)NC2=O)C(=O)NC(CC2=CNC=N2)C(=O)N1)C(C)CC)C(=O)N1CCCC1C(=O)NC(CCCCN)C(O)=O|InChiKey: MNSSWZUIQUJZTG-UHFFFAOYSA-N|InChi: InChI=1S/C169H278N54O48S8/c1-14-86(7)130-161(264)200-101(40-22-27-55-173)163(266)220-59-31-45-117(220)157(260)213-112-79-276-279-82-115(154(257)219-133(90(11)227)166(269)223-62-33-46-118(223)156(259)201-102(167(270)271)41-23-28-56-174)211-145(248)104(66-92-71-183-83-189-92)203-151(254)111-78-275-277-80-113(152(255)216-130)210-141(244)98(48-49-120(176)228)199-155(258)116-44-32-60-221(116)164(267)109(76-225)193-126(234)74-188-159(262)132(89(10)226)218-153(256)114(212-148(251)108(75-224)207-160(263)128(84(3)4)215-147(250)106(68-122(178)230)206-162(265)131(87(8)15-2)217-158(261)119-47-34-61-222(119)165(268)129(85(5)6)214-123(231)70-175)81-278-274-77-110(149(252)198-100(51-64-273-13)143(246)204-105(67-121(177)229)146(249)196-96(42-29-57-184-168(179)180)137(240)194-95(140(243)209-111)39-21-26-54-172)208-136(239)93(37-19-24-52-170)191-125(233)73-187-135(238)103(65-91-35-17-16-18-36-91)202-139(242)97(43-30-58-185-169(181)182)195-142(245)99(50-63-272-12)192-124(232)72-186-134(237)88(9)190-144(247)107(69-127(235)236)205-138(241)94(197-150(112)253)38-20-25-53-171/h16-18,35-36,71,83-90,93-119,128-133,224-227H,14-15,19-34,37-70,72-82,170-175H2,1-13H3,(H2,176,228)(H2,177,229)(H2,178,230)(H,183,189)(H,186,237)(H,187,238)(H,188,262)(H,190,247)(H,191,233)(H,192,232)(H,193,234)(H,194,240)(H,195,245)(H,196,249)(H,197,253)(H,198,252)(H,199,258)(H,200,264)(H,201,259)(H,202,242)(H,203,254)(H,204,246)(H,205,241)(H,206,265)(H,207,263)(H,208,239)(H,209,243)(H,210,244)(H,211,248)(H,212,251)(H,213,260)(H,214,231)(H,215,250)(H,216,255)(H,217,261)(H,218,256)(H,219,257)(H,235,236)(H,270,271)(H4,179,180,184)(H4,181,182,185)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Epoprostenol} MedChemExpress|{Epoprostenol} Metabolic Enzyme/Protease|{Epoprostenol} Technical Information|{Epoprostenol} In stock|{Epoprostenol} supplier|{Epoprostenol} Cancer} |Shelf Life: ≥12 months if stored properly.PMID:35901518 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|