Product Name :
PF-03654746 Tosylate
Description:
PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms. PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer’s disease (AD).
CAS:
1039399-17-1
Molecular Weight:
494.59
Formula:
C25H32F2N2O4S
Chemical Name:
(1s,3s)-N-ethyl-3-fluoro-3-{3-fluoro-4-[(pyrrolidin-1-yl)methyl]phenyl}cyclobutane-1-carboxamide; 4-methylbenzene-1-sulfonic acid
Smiles :
CC1C=CC(=CC=1)S(O)(=O)=O.CCNC(=O)[C@@H]1C[C@](F)(C1)C1C=C(F)C(CN2CCCC2)=CC=1
InChiKey:
IKAYTZLLIWAEDV-PHNBSMHASA-N
InChi :
InChI=1S/C18H24F2N2O.C7H8O3S/c1-2-21-17(23)14-10-18(20,11-14)15-6-5-13(16(19)9-15)12-22-7-3-4-8-22;1-6-2-4-7(5-3-6)11(8,9)10/h5-6,9,14H,2-4,7-8,10-12H2,1H3,(H,21,23);2-5H,1H3,(H,8,9,10)/t14-,18+;
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms. PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer’s disease (AD).{{Dipyridamole} web|{Dipyridamole} Metabolic Enzyme/Protease|{Dipyridamole} Biological Activity|{Dipyridamole} Description|{Dipyridamole} manufacturer|{Dipyridamole} Epigenetic Reader Domain} |Product information|CAS Number: 1039399-17-1|Molecular Weight: 494.{{Guanidine} medchemexpress|{Guanidine} Metabolic Enzyme/Protease|{Guanidine} Technical Information|{Guanidine} Data Sheet|{Guanidine} custom synthesis|{Guanidine} Autophagy} 59|Formula: C25H32F2N2O4S|Chemical Name: (1s,3s)-N-ethyl-3-fluoro-3-{3-fluoro-4-[(pyrrolidin-1-yl)methyl]phenyl}cyclobutane-1-carboxamide; 4-methylbenzene-1-sulfonic acid|Smiles: CC1C=CC(=CC=1)S(O)(=O)=O.PMID:24318587 CCNC(=O)[C@@H]1C[C@](F)(C1)C1C=C(F)C(CN2CCCC2)=CC=1|InChiKey: IKAYTZLLIWAEDV-PHNBSMHASA-N|InChi: InChI=1S/C18H24F2N2O.C7H8O3S/c1-2-21-17(23)14-10-18(20,11-14)15-6-5-13(16(19)9-15)12-22-7-3-4-8-22;1-6-2-4-7(5-3-6)11(8,9)10/h5-6,9,14H,2-4,7-8,10-12H2,1H3,(H,21,23);2-5H,1H3,(H,8,9,10)/t14-,18+;|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : ≥ 8.4 mg/mL (16.98 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|