Product Name :
Pomalidomide-PEG6-NH2 hydrochloride
Description:
Pomalidomide-PEG6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology.
CAS:
2341841-01-6
Molecular Weight:
574.02
Formula:
C25H36ClN3O10
Chemical Name:
4-[(17-amino-3, 6, 9, 12, 15-pentaoxaheptadecan-1-yl)oxy]-2-(2, 6-dioxopiperidin-3-yl)-2, 3-dihydro-1H-isoindole-1, 3-dione hydrochloride
Smiles :
Cl.NCCOCCOCCOCCOCCOCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
InChiKey:
MWEFMNTVJQCCJU-UHFFFAOYSA-N
InChi :
InChI=1S/C25H35N3O10.ClH/c26-6-7-33-8-9-34-10-11-35-12-13-36-14-15-37-16-17-38-20-3-1-2-18-22(20)25(32)28(24(18)31)19-4-5-21(29)27-23(19)30;/h1-3,19H,4-17,26H2,(H,27,29,30);1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Amlodipine besylate} site|{Amlodipine besylate} Calcium Channel|{Amlodipine besylate} Technical Information|{Amlodipine besylate} In stock|{Amlodipine besylate} manufacturer|{Amlodipine besylate} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Pyridostigmine} site|{Pyridostigmine} Cholinesterase (ChE)|{Pyridostigmine} Protocol|{Pyridostigmine} Purity|{Pyridostigmine} manufacturer|{Pyridostigmine} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32515477
Additional information:
Pomalidomide-PEG6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology.|Product information|CAS Number: 2341841-01-6|Molecular Weight: 574.02|Formula: C25H36ClN3O10|Chemical Name: 4-[(17-amino-3, 6, 9, 12, 15-pentaoxaheptadecan-1-yl)oxy]-2-(2, 6-dioxopiperidin-3-yl)-2, 3-dihydro-1H-isoindole-1, 3-dione hydrochloride|Smiles: Cl.NCCOCCOCCOCCOCCOCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O|InChiKey: MWEFMNTVJQCCJU-UHFFFAOYSA-N|InChi: InChI=1S/C25H35N3O10.ClH/c26-6-7-33-8-9-34-10-11-35-12-13-36-14-15-37-16-17-38-20-3-1-2-18-22(20)25(32)28(24(18)31)19-4-5-21(29)27-23(19)30;/h1-3,19H,4-17,26H2,(H,27,29,30);1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|