Product Name :
Doxapram (hydrochloride hydrate)

Description:
Doxapram is a respiratory stimulant. Administered intravenously, Doxapram stimulates an increase in tidal volume and respiratory rate. Doxapram stimulates chemoreceptors in the carotid bodies of the carotid arteries, which in turn, stimulates the respiratory centre in the brain stem. Doxapram induced changes in the electrophysiological properties of pre-inspiratory and inspiratory neurones. Results suggest that respiratory activity enhancement was likely to be induced via effects on the potassium channels of pre-inspiratory and inspiratory neurones and indicate the central actions of doxapram.

CAS:
7081-53-0

Molecular Weight:
432.98

Formula:
C24H33ClN2O3

Chemical Name:
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one hydrate hydrochloride

Smiles :
O.Cl.CCN1CC(CCN2CCOCC2)C(C1=O)(C1C=CC=CC=1)C1C=CC=CC=1

InChiKey:
ZOMBFZRWMLIDPX-UHFFFAOYSA-N

InChi :
InChI=1S/C24H30N2O2.ClH.H2O/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;;/h3-12,22H,2,13-19H2,1H3;1H;1H2

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Doxapram is a respiratory stimulant. Administered intravenously, Doxapram stimulates an increase in tidal volume and respiratory rate. Doxapram stimulates chemoreceptors in the carotid bodies of the carotid arteries, which in turn, stimulates the respiratory centre in the brain stem. Doxapram induced changes in the electrophysiological properties of pre-inspiratory and inspiratory neurones. Results suggest that respiratory activity enhancement was likely to be induced via effects on the potassium channels of pre-inspiratory and inspiratory neurones and indicate the central actions of doxapram.|Product information|CAS Number: 7081-53-0|Molecular Weight: 432.98|Formula: C24H33ClN2O3|Synonym:|Dopram hydrochloride hydrate|Stimulex hydrochloride hydrate|Respiram hydrochloride hydrate|Chemical Name: 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one hydrate hydrochloride|Smiles: O.Cl.CCN1CC(CCN2CCOCC2)C(C1=O)(C1C=CC=CC=1)C1C=CC=CC=1|InChiKey: ZOMBFZRWMLIDPX-UHFFFAOYSA-N|InChi: InChI=1S/C24H30N2O2.Nile Red Autophagy ClH.1,4-Dibromobenzene-d4 manufacturer H2O/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;;/h3-12,22H,2,13-19H2,1H3;1H;1H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32011599 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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