Product Name :
A-802715

Description:
A802715 is a methylxanthine derivative. A802715 has a TD50 (toxic dose of 50%) of 0.9-1.1 mM.

CAS:
107767-58-8

Molecular Weight:
322.40

Formula:
C16H26N4O3

Chemical Name:
1-(5-hydroxy-5-methylhexyl)-3-methyl-7-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

Smiles :
CN1C2N=CN(CCC)C=2C(=O)N(CCCCC(C)(C)O)C1=O

InChiKey:
SBKAARSDXHSHSM-UHFFFAOYSA-N

InChi :
InChI=1S/C16H26N4O3/c1-5-9-19-11-17-13-12(19)14(21)20(15(22)18(13)4)10-7-6-8-16(2,3)23/h11,23H,5-10H2,1-4H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Inclisiran Formula

Additional information:
A802715 is a methylxanthine derivative.Surfactin medchemexpress A802715 has a TD50 (toxic dose of 50%) of 0.PMID:33052706 9-1.1 mM.|Product information|CAS Number: 107767-58-8|Molecular Weight: 322.40|Formula: C16H26N4O3|Chemical Name: 1-(5-hydroxy-5-methylhexyl)-3-methyl-7-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione|Smiles: CN1C2N=CN(CCC)C=2C(=O)N(CCCCC(C)(C)O)C1=O|InChiKey: SBKAARSDXHSHSM-UHFFFAOYSA-N|InChi: InChI=1S/C16H26N4O3/c1-5-9-19-11-17-13-12(19)14(21)20(15(22)18(13)4)10-7-6-8-16(2,3)23/h11,23H,5-10H2,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 190 mg/mL (589.33 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|The toxicity of the methylxanthine derivative A802715 is determined against the two human melanoma lines, Be11 and MeWo, and against the two human squamous cell carcinoma lines, 4197 and 4451, by vital dye staining assay. A802715 has a TD50 of 0.9-1.1 mM and is the most toxic. In p53 wt cells BrdU incorporations show that the irradiation-induced suppression of S-phase entry is strongly enhanced by A802715. A802715 prolongs the G2/M block or remain ineffective depending on the p53 status of the cell line.|References:|Bohm L, et al. Influence of pentoxifylline, A-802710, propentofylline and A-802715 (Hoechst) on the expression of cell cycle blocks and S-phase content after irradiation damage. Biochim Biophys Acta. 2000 Dec 11;1499(1-2):1-10.Products are for research use only. Not for human use.|

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