Product Name :
CeMMEC13
Description:
CeMMEC13 is a potent inhibitor of TAF1 (2) bromodomain, with an IC50 of 2.1 μM.
CAS:
1790895-25-8
Molecular Weight:
336.34
Formula:
C19H16N2O4
Chemical Name:
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide
Smiles :
CN1C2C=CC=CC=2C(=CC1=O)C(=O)NC1C=C2OCCOC2=CC=1
InChiKey:
NXKBPGZQDHACPZ-UHFFFAOYSA-N
InChi :
InChI=1S/C19H16N2O4/c1-21-15-5-3-2-4-13(15)14(11-18(21)22)19(23)20-12-6-7-16-17(10-12)25-9-8-24-16/h2-7,10-11H,8-9H2,1H3,(H,20,23)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
CeMMEC13 is a potent inhibitor of TAF1 (2) bromodomain, with an IC50 of 2.1 μM.|Product information|CAS Number: 1790895-25-8|Molecular Weight: 336.34|Formula: C19H16N2O4|Chemical Name: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide|Smiles: CN1C2C=CC=CC=2C(=CC1=O)C(=O)NC1C=C2OCCOC2=CC=1|InChiKey: NXKBPGZQDHACPZ-UHFFFAOYSA-N|InChi: InChI=1S/C19H16N2O4/c1-21-15-5-3-2-4-13(15)14(11-18(21)22)19(23)20-12-6-7-16-17(10-12)25-9-8-24-16/h2-7,10-11H,8-9H2,1H3,(H,20,23)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 30 mg/mL (89.20 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Liothyronine Autophagy |Shelf Life: ≥12 months if stored properly.Relugolix Biological Activity |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33353440 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|CeMMEC13 is a potent inhibitor of TAF1 (2) bromodomain, with an IC50 of 2.1 μM. CeMMEC13 shows little or no effects on REDNESS, BRD4, CREBBP. CeMMEC13 (0-20 μM) in combination with (S)-JQ1 increases RFP expression in REDS3 cells and is effective reducing the viability of H23 and THP1 cells, better than that of single treatment.|Products are for research use only. Not for human use.|