Product Name :
Ceapin-A7
Description:
Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings.
CAS:
2323027-38-7
Molecular Weight:
470.32
Formula:
C20H12F6N4O3
Chemical Name:
N-(1-{[2,4-bis(trifluoromethyl)phenyl]methyl}-1H-pyrazol-4-yl)-5-(furan-2-yl)-1,2-oxazole-3-carboxamide
Smiles :
O=C(NC1C=NN(CC2=CC=C(C=C2C(F)(F)F)C(F)(F)F)C=1)C1C=C(ON=1)C1=CC=CO1
InChiKey:
UJTDYOXTXGBHEG-UHFFFAOYSA-N
InChi :
InChI=1S/C20H12F6N4O3/c21-19(22,23)12-4-3-11(14(6-12)20(24,25)26)9-30-10-13(8-27-30)28-18(31)15-7-17(33-29-15)16-2-1-5-32-16/h1-8,10H,9H2,(H,28,31)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings.|Product information|CAS Number: 2323027-38-7|Molecular Weight: 470.32|Formula: C20H12F6N4O3|Chemical Name: N-(1-{[2,4-bis(trifluoromethyl)phenyl]methyl}-1H-pyrazol-4-yl)-5-(furan-2-yl)-1,2-oxazole-3-carboxamide|Smiles: O=C(NC1C=NN(CC2=CC=C(C=C2C(F)(F)F)C(F)(F)F)C=1)C1C=C(ON=1)C1=CC=CO1|InChiKey: UJTDYOXTXGBHEG-UHFFFAOYSA-N|InChi: InChI=1S/C20H12F6N4O3/c21-19(22,23)12-4-3-11(14(6-12)20(24,25)26)9-30-10-13(8-27-30)28-18(31)15-7-17(33-29-15)16-2-1-5-32-16/h1-8,10H,9H2,(H,28,31)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (212.{{Riboflavin} medchemexpress|{Riboflavin} Anti-infection|{Riboflavin} Biological Activity|{Riboflavin} Description|{Riboflavin} manufacturer|{Riboflavin} Cancer} 62 mM; Need ultrasonic).{{Ritlecitinib} medchemexpress|{Ritlecitinib} Stem Cell/Wnt|{Ritlecitinib} Purity & Documentation|{Ritlecitinib} Description|{Ritlecitinib} custom synthesis|{Ritlecitinib} Epigenetic Reader Domain} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23398362 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Ceapin-A7 sensitizes cells to ER stress. Ceapin (0.6-18.9 μM; 4.5 hours) selectively inhibits ATF6α but not ATF6β.|Products are for research use only. Not for human use.|