Product Name :
(R)-Simurosertib
Description:
(R)-Simurosertib ((R)-TAK-931) is the (R)-enantiomer of Simurosertib. Simurosertib (TAK-931) is an orally active, selective and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC50 of <0.3 nM .
CAS:
1330782-69-8
Molecular Weight:
341.43
Formula:
C17H19N5OS
Chemical Name:
2-[(2R)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)-3H,4H-thieno[3,2-d]pyrimidin-4-one
Smiles :
CC1NN=CC=1C1=CC2N=C(NC(=O)C=2S1)[C@H]1CC2CCN1CC2
InChiKey:
XGVXKJKTISMIOW-CYBMUJFWSA-N
InChi :
InChI=1S/C17H19N5OS/c1-9-11(8-18-21-9)14-7-12-15(24-14)17(23)20-16(19-12)13-6-10-2-4-22(13)5-3-10/h7-8,10,13H,2-6H2,1H3,(H,18,21)(H,19,20,23)/t13-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Anagliptin} web|{Anagliptin} Metabolic Enzyme/Protease|{Anagliptin} Protocol|{Anagliptin} Formula|{Anagliptin} manufacturer|{Anagliptin} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
(R)-Simurosertib ((R)-TAK-931) is the (R)-enantiomer of Simurosertib. Simurosertib (TAK-931) is an orally active, selective and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC50 of Product information|CAS Number: 1330782-69-8|Molecular Weight: 341.43|Formula: C17H19N5OS|Chemical Name: 2-[(2R)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)-3H,4H-thieno[3,2-d]pyrimidin-4-one|Smiles: CC1NN=CC=1C1=CC2N=C(NC(=O)C=2S1)[C@H]1CC2CCN1CC2|InChiKey: XGVXKJKTISMIOW-CYBMUJFWSA-N|InChi: InChI=1S/C17H19N5OS/c1-9-11(8-18-21-9)14-7-12-15(24-14)17(23)20-16(19-12)13-6-10-2-4-22(13)5-3-10/h7-8,10,13H,2-6H2,1H3,(H,18,21)(H,19,20,23)/t13-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 75 mg/mL (219.{{Amantadine} MedChemExpress|{Amantadine} Apoptosis|{Amantadine} Protocol|{Amantadine} In stock|{Amantadine} supplier|{Amantadine} Autophagy} 66 mM; Need ultrasonic).PMID:36014399 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|