Product Name :
Acivicin hydrochloride
Description:
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties.
CAS:
161922-40-3
Molecular Weight:
215.03
Formula:
C5H8Cl2N2O3
Chemical Name:
(2S)-2-amino-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid hydrochloride
Smiles :
Cl.N[C@@H]([C@@H]1CC(Cl)=NO1)C(O)=O
InChiKey:
IXBPTDHBIYEQHX-QYEIVYHBSA-N
InChi :
InChI=1S/C5H7ClN2O3.ClH/c6-3-1-2(11-8-3)4(7)5(9)10;/h2,4H,1,7H2,(H,9,10);1H/t2-,4-;/m0./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Isosulfan blue} web|{Isosulfan blue} {Fluorescent Dye}|{Isosulfan blue} Protocol|{Isosulfan blue} In Vitro|{Isosulfan blue} supplier|{Isosulfan blue} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Omidenepag} MedChemExpress|{Omidenepag} Prostaglandin Receptor|{Omidenepag} Technical Information|{Omidenepag} References|{Omidenepag} manufacturer|{Omidenepag} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23916866
Additional information:
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties.|Product information|CAS Number: 161922-40-3|Molecular Weight: 215.03|Formula: C5H8Cl2N2O3|Chemical Name: (2S)-2-amino-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid hydrochloride|Smiles: Cl.N[C@@H]([C@@H]1CC(Cl)=NO1)C(O)=O|InChiKey: IXBPTDHBIYEQHX-QYEIVYHBSA-N|InChi: InChI=1S/C5H7ClN2O3.ClH/c6-3-1-2(11-8-3)4(7)5(9)10;/h2,4H,1,7H2,(H,9,10);1H/t2-,4-;/m0./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Acivicin hydrochloride (AT-125 hydrochloride; 0.1-50 μM; 5 days) has an IC50 of 0.7 μM in human HepG2 cells.|In Vivo:|Acivicin hydrochloride (AT-125 hydrochloride; 5 mg/kg; IP; twice weekly) reduces urinary γ-GT by 70-78%.|Products are for research use only. Not for human use.|