Product Name :
ML-290
Description:
ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM. ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.
CAS:
1482500-76-4
Molecular Weight:
506.49
Formula:
C24H21F3N2O5S
Chemical Name:
2-(propan-2-yloxy)-N-{2-[(3-trifluoromethanesulfonylphenyl)carbamoyl]phenyl}benzamide
Smiles :
CC(C)OC1=CC=CC=C1C(=O)NC1=CC=CC=C1C(=O)NC1=CC(=CC=C1)S(=O)(=O)C(F)(F)F
InChiKey:
RSYHJSDOGMSLDH-UHFFFAOYSA-N
InChi :
InChI=1S/C24H21F3N2O5S/c1-15(2)34-21-13-6-4-11-19(21)23(31)29-20-12-5-3-10-18(20)22(30)28-16-8-7-9-17(14-16)35(32,33)24(25,26)27/h3-15H,1-2H3,(H,28,30)(H,29,31)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ticagrelor} medchemexpress|{Ticagrelor} GPCR/G Protein|{Ticagrelor} Purity & Documentation|{Ticagrelor} References|{Ticagrelor} supplier|{Ticagrelor} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM. ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.|Product information|CAS Number: 1482500-76-4|Molecular Weight: 506.49|Formula: C24H21F3N2O5S|Chemical Name: 2-(propan-2-yloxy)-N-{2-[(3-trifluoromethanesulfonylphenyl)carbamoyl]phenyl}benzamide|Smiles: CC(C)OC1=CC=CC=C1C(=O)NC1=CC=CC=C1C(=O)NC1=CC(=CC=C1)S(=O)(=O)C(F)(F)F|InChiKey: RSYHJSDOGMSLDH-UHFFFAOYSA-N|InChi: InChI=1S/C24H21F3N2O5S/c1-15(2)34-21-13-6-4-11-19(21)23(31)29-20-12-5-3-10-18(20)22(30)28-16-8-7-9-17(14-16)35(32,33)24(25,26)27/h3-15H,1-2H3,(H,28,30)(H,29,31)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{NPX800} MedChemExpress|{NPX800} Metabolic Enzyme/Protease|{NPX800} Protocol|{NPX800} In stock|{NPX800} supplier|{NPX800} Epigenetics} |Shelf Life: ≥12 months if stored properly.PMID:23399686 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM. ML290 (5 μM) shows anti-fibrotic, relaxin-like gene expression at 24 and 72 h in activated human hepatic stellate cells.|Products are for research use only. Not for human use.|