Product Name :
KL044
Description:
KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity.
CAS:
1801856-93-8
Molecular Weight:
359.81
Formula:
C21H14ClN3O
Chemical Name:
2-(9H-carbazol-9-yl)-N-(2-chloro-6-cyanophenyl)acetamide
Smiles :
N#CC1=CC=CC(Cl)=C1NC(=O)CN1C2=CC=CC=C2C2=CC=CC=C12
InChiKey:
ZDAKKNHUWVTCRS-UHFFFAOYSA-N
InChi :
InChI=1S/C21H14ClN3O/c22-17-9-5-6-14(12-23)21(17)24-20(26)13-25-18-10-3-1-7-15(18)16-8-2-4-11-19(16)25/h1-11H,13H2,(H,24,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity.|Product information|CAS Number: 1801856-93-8|Molecular Weight: 359.81|Formula: C21H14ClN3O|Chemical Name: 2-(9H-carbazol-9-yl)-N-(2-chloro-6-cyanophenyl)acetamide|Smiles: N#CC1=CC=CC(Cl)=C1NC(=O)CN1C2=CC=CC=C2C2=CC=CC=C12|InChiKey: ZDAKKNHUWVTCRS-UHFFFAOYSA-N|InChi: InChI=1S/C21H14ClN3O/c22-17-9-5-6-14(12-23)21(17)24-20(26)13-25-18-10-3-1-7-15(18)16-8-2-4-11-19(16)25/h1-11H,13H2,(H,24,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (277.92 mM; Need ultrasonic).{{IL-4 Protein, Mouse} web|{IL-4 Protein, Mouse} Protocol|{IL-4 Protein, Mouse} In Vitro|{IL-4 Protein, Mouse} supplier|{IL-4 Protein, Mouse} Autophagy} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Digitonin} medchemexpress|{Digitonin} Biological Activity|{Digitonin} Data Sheet|{Digitonin} supplier|{Digitonin} Autophagy} |Shelf Life: ≥12 months if stored properly.PMID:33679749 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|KL044 (0-3.7 μM; 8 h) effectively stabilizes the CRY1-LUC fusion protein without affecting the stability of LUC in the HEK293 stable cell line.|Products are for research use only. Not for human use.|