Product Name :
Apovincamine
Description:
Apovincamine (cis-Apovincamine) is an indole alkaloid isolated from the Malaysian Alstonia pneumatophora (Apocynaceae). Apovincamine shows anti-melanogenesis activity.
CAS:
4880-92-6
Molecular Weight:
336.43
Formula:
C21H24N2O2
Chemical Name:
methyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.0²,⁷.0⁸,¹⁸.0¹⁵,¹⁹]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate
Smiles :
CC[C@@]12CCCN3CCC4=C([C@H]13)N(C(=C2)C(=O)OC)C1=CC=CC=C41
InChiKey:
OZDNDGXASTWERN-CTNGQTDRSA-N
InChi :
InChI=1S/C21H24N2O2/c1-3-21-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(18(15)19(21)22)17(13-21)20(24)25-2/h4-5,7-8,13,19H,3,6,9-12H2,1-2H3/t19-,21+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Penicillamine} site|{Penicillamine} Apoptosis|{Penicillamine} Purity & Documentation|{Penicillamine} Purity|{Penicillamine} manufacturer|{Penicillamine} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Maropitant} MedChemExpress|{Maropitant} Neuronal Signaling|{Maropitant} Technical Information|{Maropitant} Description|{Maropitant} manufacturer|{Maropitant} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33679749
Additional information:
Apovincamine (cis-Apovincamine) is an indole alkaloid isolated from the Malaysian Alstonia pneumatophora (Apocynaceae). Apovincamine shows anti-melanogenesis activity.|Product information|CAS Number: 4880-92-6|Molecular Weight: 336.43|Formula: C21H24N2O2|Chemical Name: methyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.0²,⁷.0⁸,¹⁸.0¹⁵,¹⁹]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate|Smiles: CC[C@@]12CCCN3CCC4=C([C@H]13)N(C(=C2)C(=O)OC)C1=CC=CC=C41|InChiKey: OZDNDGXASTWERN-CTNGQTDRSA-N|InChi: InChI=1S/C21H24N2O2/c1-3-21-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(18(15)19(21)22)17(13-21)20(24)25-2/h4-5,7-8,13,19H,3,6,9-12H2,1-2H3/t19-,21+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Apovincamine (cis-Apovincamine; 6.3, 12.5, 25, 50, 100 μM) dose-dependently inhibits cells viability with an IC50 of 49.8 μM and shows anti-melanogenesis in B16 mouse melanoma cells.|Products are for research use only. Not for human use.|