Product Name :
Nesolicaftor

Description:
Nesolicaftor (PTI-428) is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier that increases CFTR expression.

CAS:
1953130-87-4

Molecular Weight:
354.36

Formula:
C18H18N4O4

Chemical Name:
N-(trans-3-[5-[(1R)-1-hydroxyethyl]-1,3,4-oxadiazol-2-yl]cyclobutyl)-3-phenyl-1,2-oxazole-5-carboxamide

Smiles :
C[C@@H](O)C1=NN=C(O1)[C@@H]1C[C@H](C1)NC(=O)C1=CC(=NO1)C1C=CC=CC=1

InChiKey:
XPEHHUISIBFLHX-RAIGVLPGSA-N

InChi :
InChI=1S/C18H18N4O4/c1-10(23)17-20-21-18(25-17)12-7-13(8-12)19-16(24)15-9-14(22-26-15)11-5-3-2-4-6-11/h2-6,9-10,12-13,23H,7-8H2,1H3,(H,19,24)/t10-,12-,13-/m1/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Mirikizumab} web|{Mirikizumab} Immunology/Inflammation|{Mirikizumab} Purity & Documentation|{Mirikizumab} References|{Mirikizumab} custom synthesis|{Mirikizumab} Epigenetic Reader Domain}

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Nesolicaftor (PTI-428) is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier that increases CFTR expression.{{D-Pantothenic acid} medchemexpress|{D-Pantothenic acid} Endogenous Metabolite|{D-Pantothenic acid} Purity & Documentation|{D-Pantothenic acid} Description|{D-Pantothenic acid} supplier|{D-Pantothenic acid} Cancer} |Product information|CAS Number: 1953130-87-4|Molecular Weight: 354.36|Formula: C18H18N4O4|Synonym:|PTI-428|PTI 428|PTI428|Chemical Name: N-(trans-3-[5-[(1R)-1-hydroxyethyl]-1,3,4-oxadiazol-2-yl]cyclobutyl)-3-phenyl-1,2-oxazole-5-carboxamide|Smiles: C[C@@H](O)C1=NN=C(O1)[C@@H]1C[C@H](C1)NC(=O)C1=CC(=NO1)C1C=CC=CC=1|InChiKey: XPEHHUISIBFLHX-RAIGVLPGSA-N|InChi: InChI=1S/C18H18N4O4/c1-10(23)17-20-21-18(25-17)12-7-13(8-12)19-16(24)15-9-14(22-26-15)11-5-3-2-4-6-11/h2-6,9-10,12-13,23H,7-8H2,1H3,(H,19,24)/t10-,12-,13-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO: 71 mg/mL(200.PMID:23829314 36 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Marjolein Mijnders, et al. Curr Opin Pharmacol. 2017 Jun;34:83-90.Products are for research use only. Not for human use.|

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