Product Name :
NH2-PEG4-CH2CH2COOH
Description:
NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
663921-15-1
Molecular Weight:
265.30
Formula:
C11H23NO6
Chemical Name:
1-amino-3,6,9,12-tetraoxapentadecan-15-oic acid
Smiles :
NCCOCCOCCOCCOCCC(O)=O
InChiKey:
DKUZHSDZSMQOGQ-UHFFFAOYSA-N
InChi :
InChI=1S/C11H23NO6/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h1-10,12H2,(H,13,14)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 663921-15-1|Molecular Weight: 265.30|Formula: C11H23NO6|Chemical Name: 1-amino-3,6,9,12-tetraoxapentadecan-15-oic acid|Smiles: NCCOCCOCCOCCOCCC(O)=O|InChiKey: DKUZHSDZSMQOGQ-UHFFFAOYSA-N|InChi: InChI=1S/C11H23NO6/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h1-10,12H2,(H,13,14)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ibezapolstat} medchemexpress|{Ibezapolstat} Anti-infection|{Ibezapolstat} Purity & Documentation|{Ibezapolstat} In Vivo|{Ibezapolstat} supplier|{Ibezapolstat} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.{{Tirabrutinib} web|{Tirabrutinib} Protein Tyrosine Kinase/RTK|{Tirabrutinib} Purity & Documentation|{Tirabrutinib} Description|{Tirabrutinib} custom synthesis|{Tirabrutinib} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23672196 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|