Product Name :
RT-AM
Description:
RT-AM is a pro-drug real thiol. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
CAS:
2280796-94-1
Molecular Weight:
555.49
Formula:
C26H25N3O11
Chemical Name:
(acetyloxy)methyl 2-[(2E)-N-{2-[(acetyloxy)methoxy]-2-oxoethyl}-3-[7-(azetidin-1-yl)-2-oxo-2H-chromen-3-yl]-2-cyanoprop-2-enamido]acetate
Smiles :
CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)C(=O)/C(=C/C1=CC2=CC=C(C=C2OC1=O)N1CCC1)/C#N
InChiKey:
CLCCMBNDDZVBCA-AWQFTUOYSA-N
InChi :
InChI=1S/C26H25N3O11/c1-16(30)36-14-38-23(32)12-29(13-24(33)39-15-37-17(2)31)25(34)20(11-27)9-19-8-18-4-5-21(28-6-3-7-28)10-22(18)40-26(19)35/h4-5,8-10H,3,6-7,12-15H2,1-2H3/b20-9+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Batoclimab} web|{Batoclimab} Technical Information|{Batoclimab} Formula|{Batoclimab} custom synthesis|{Batoclimab} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
RT-AM is a pro-drug real thiol. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.|Product information|CAS Number: 2280796-94-1|Molecular Weight: 555.49|Formula: C26H25N3O11|Chemical Name: (acetyloxy)methyl 2-[(2E)-N-{2-[(acetyloxy)methoxy]-2-oxoethyl}-3-[7-(azetidin-1-yl)-2-oxo-2H-chromen-3-yl]-2-cyanoprop-2-enamido]acetate|Smiles: CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)C(=O)/C(=C/C1=CC2=CC=C(C=C2OC1=O)N1CCC1)/C#N|InChiKey: CLCCMBNDDZVBCA-AWQFTUOYSA-N|InChi: InChI=1S/C26H25N3O11/c1-16(30)36-14-38-23(32)12-29(13-24(33)39-15-37-17(2)31)25(34)20(11-27)9-19-8-18-4-5-21(28-6-3-7-28)10-22(18)40-26(19)35/h4-5,8-10H,3,6-7,12-15H2,1-2H3/b20-9+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Revefenacin} medchemexpress|{Revefenacin} Neuronal Signaling|{Revefenacin} Biological Activity|{Revefenacin} In Vivo|{Revefenacin} supplier|{Revefenacin} Autophagy} |Shelf Life: ≥12 months if stored properly.PMID:24140575 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|To enhance the cell permeability of Real Thiol, the carboxylic acid groups is converted to acetoxymethyl (AM) esters, which are readily hydrolysed by esterases to regenerate Real Thiol inside cells. For cells treated with the RT-AM, real-time ratiometric images of the rapid changes of intracellular GSH concentrations in single cells can be generated by dividing the fluorescence intensity values for the 405 nm channel by the 488 nm channel at each corresponding pixel.|Products are for research use only. Not for human use.|