Product Name :
Glisoxepide
Description:
Glisoxepide, a sulphonamide derivative, is an orally available nonselective K(ATP) channel blocker, with antihyperglycemic activity and cardiovascular regulation effect.
CAS:
25046-79-1
Molecular Weight:
449.52
Formula:
C20H27N5O5S
Chemical Name:
N-{2-[4-({[(azepan-1-yl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-5-methyl-1,2-oxazole-3-carboxamide
Smiles :
CC1=CC(=NO1)C(=O)NCCC1C=CC(=CC=1)S(=O)(=O)NC(=O)NN1CCCCCC1
InChiKey:
ZKUDBRCEOBOWLF-UHFFFAOYSA-N
InChi :
InChI=1S/C20H27N5O5S/c1-15-14-18(23-30-15)19(26)21-11-10-16-6-8-17(9-7-16)31(28,29)24-20(27)22-25-12-4-2-3-5-13-25/h6-9,14H,2-5,10-13H2,1H3,(H,21,26)(H2,22,24,27)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Hydroxychloroquine} site|{Hydroxychloroquine} Immunology/Inflammation|{Hydroxychloroquine} Protocol|{Hydroxychloroquine} Purity|{Hydroxychloroquine} manufacturer|{Hydroxychloroquine} Autophagy}
Additional information:
Glisoxepide, a sulphonamide derivative, is an orally available nonselective K(ATP) channel blocker, with antihyperglycemic activity and cardiovascular regulation effect.{{Sabizabulin} MedChemExpress|{Sabizabulin} Apoptosis|{Sabizabulin} Purity & Documentation|{Sabizabulin} Formula|{Sabizabulin} manufacturer|{Sabizabulin} Autophagy} |Product information|CAS Number: 25046-79-1|Molecular Weight: 449.PMID:23381601 52|Formula: C20H27N5O5S|Chemical Name: N-{2-[4-({[(azepan-1-yl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-5-methyl-1,2-oxazole-3-carboxamide|Smiles: CC1=CC(=NO1)C(=O)NCCC1C=CC(=CC=1)S(=O)(=O)NC(=O)NN1CCCCCC1|InChiKey: ZKUDBRCEOBOWLF-UHFFFAOYSA-N|InChi: InChI=1S/C20H27N5O5S/c1-15-14-18(23-30-15)19(26)21-11-10-16-6-8-17(9-7-16)31(28,29)24-20(27)22-25-12-4-2-3-5-13-25/h6-9,14H,2-5,10-13H2,1H3,(H,21,26)(H2,22,24,27)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Glisoxepide inhibits the uptake of bile acids into isolated rat hepatocytes. Glisoxepide noncompetitively inhibits the cholate uptake with a Ki of 200 μM.|Products are for research use only. Not for human use.|