Product Name :
IK1 inhibitor PA-6
Description:
IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia.
CAS:
500715-03-7
Molecular Weight:
492.61
Formula:
C31H32N4O2
Chemical Name:
N’-(4-{[5-(4-{[amino(phenyl)methylidene]amino}phenoxy)pentyl]oxy}phenyl)benzenecarboximidamide
Smiles :
NC(=NC1C=CC(=CC=1)OCCCCCOC1C=CC(=CC=1)N=C(N)C1C=CC=CC=1)C1C=CC=CC=1
InChiKey:
PETGITKEGWIZEL-UHFFFAOYSA-N
InChi :
InChI=1S/C31H32N4O2/c32-30(24-10-4-1-5-11-24)34-26-14-18-28(19-15-26)36-22-8-3-9-23-37-29-20-16-27(17-21-29)35-31(33)25-12-6-2-7-13-25/h1-2,4-7,10-21H,3,8-9,22-23H2,(H2,32,34)(H2,33,35)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Anti-Spike-RBD mAb} medchemexpress|{Anti-Spike-RBD mAb} Anti-infection|{Anti-Spike-RBD mAb} Technical Information|{Anti-Spike-RBD mAb} In Vitro|{Anti-Spike-RBD mAb} custom synthesis|{Anti-Spike-RBD mAb} Autophagy}
Additional information:
IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia.|Product information|CAS Number: 500715-03-7|Molecular Weight: 492.61|Formula: C31H32N4O2|Chemical Name: N’-(4-{[5-(4-{[amino(phenyl)methylidene]amino}phenoxy)pentyl]oxy}phenyl)benzenecarboximidamide|Smiles: NC(=NC1C=CC(=CC=1)OCCCCCOC1C=CC(=CC=1)N=C(N)C1C=CC=CC=1)C1C=CC=CC=1|InChiKey: PETGITKEGWIZEL-UHFFFAOYSA-N|InChi: InChI=1S/C31H32N4O2/c32-30(24-10-4-1-5-11-24)34-26-14-18-28(19-15-26)36-22-8-3-9-23-37-29-20-16-27(17-21-29)35-31(33)25-12-6-2-7-13-25/h1-2,4-7,10-21H,3,8-9,22-23H2,(H2,32,34)(H2,33,35)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (253.{{Veratridine} MedChemExpress|{Veratridine} Sodium Channel|{Veratridine} Protocol|{Veratridine} References|{Veratridine} supplier|{Veratridine} Epigenetics} 75 mM; Need ultrasonic).PMID:23667820 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|