Product Name :
N-methyl-N’-methyl-O-(m-PEG4)-O’-(azide-PEG4)-Cy5
Description:
N-methyl-N’-methyl-O-(m-PEG4)-O’-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2107273-56-1
Molecular Weight:
886.51
Formula:
C46H68ClN5O10
Chemical Name:
2-[(1E,3E)-5-{5-[(14-azido-3,6,9,12-tetraoxatetradecan-1-yl)oxy]-1,3,3-trimethyl-2,3-dihydro-1H-indol-2-ylidene}penta-1,3-dien-1-yl]-1,3,3-trimethyl-5-(2,5,8,11-tetraoxatridecan-13-yloxy)-3H-indol-1-ium chloride
Smiles :
[Cl-].COCCOCCOCCOCCOC1=CC2=C(C=C1)[N+](C)=C(/C=C/C=C/C=C1N(C)C3=CC=C(C=C3C1(C)C)OCCOCCOCCOCCOCCN=[N+]=[N-])C2(C)C
InChiKey:
CKLDNAAAZOJWFY-UHFFFAOYSA-M
InChi :
InChI=1S/C46H68N5O10.ClH/c1-45(2)39-35-37(60-33-31-58-29-27-56-24-23-54-20-19-52-7)13-15-41(39)50(5)43(45)11-9-8-10-12-44-46(3,4)40-36-38(14-16-42(40)51(44)6)61-34-32-59-30-28-57-26-25-55-22-21-53-18-17-48-49-47;/h8-16,35-36H,17-34H2,1-7H3;1H/q+1;/p-1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
N-methyl-N’-methyl-O-(m-PEG4)-O’-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 2107273-56-1|Molecular Weight: 886.51|Formula: C46H68ClN5O10|Chemical Name: 2-[(1E,3E)-5-{5-[(14-azido-3,6,9,12-tetraoxatetradecan-1-yl)oxy]-1,3,3-trimethyl-2,3-dihydro-1H-indol-2-ylidene}penta-1,3-dien-1-yl]-1,3,3-trimethyl-5-(2,5,8,11-tetraoxatridecan-13-yloxy)-3H-indol-1-ium chloride|Smiles: [Cl-].{{Trovafloxacin} MedChemExpress|{Trovafloxacin} Bacterial|{Trovafloxacin} Purity & Documentation|{Trovafloxacin} References|{Trovafloxacin} manufacturer|{Trovafloxacin} Epigenetics} COCCOCCOCCOCCOC1=CC2=C(C=C1)[N+](C)=C(/C=C/C=C/C=C1N(C)C3=CC=C(C=C3C1(C)C)OCCOCCOCCOCCOCCN=[N+]=[N-])C2(C)C|InChiKey: CKLDNAAAZOJWFY-UHFFFAOYSA-M|InChi: InChI=1S/C46H68N5O10.{{IL-2 Protein, Human} web|{IL-2 Protein, Human} Protocol|{IL-2 Protein, Human} In Vitro|{IL-2 Protein, Human} custom synthesis|{IL-2 Protein, Human} Autophagy} ClH/c1-45(2)39-35-37(60-33-31-58-29-27-56-24-23-54-20-19-52-7)13-15-41(39)50(5)43(45)11-9-8-10-12-44-46(3,4)40-36-38(14-16-42(40)51(44)6)61-34-32-59-30-28-57-26-25-55-22-21-53-18-17-48-49-47;/h8-16,35-36H,17-34H2,1-7H3;1H/q+1;/p-1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24282960 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|