Product Name :
Quadrol

Description:
Quadrol is an immunostimulant and has been implicated as a potentially useful agent in accelerated wound healing.

CAS:
102-60-3

Molecular Weight:
292.41

Formula:
C14H32N2O4

Chemical Name:
1-({2-[bis(2-hydroxypropyl)amino]ethyl}(2-hydroxypropyl)amino)propan-2-ol

Smiles :
CC(O)CN(CC(C)O)CCN(CC(C)O)CC(C)O

InChiKey:
NSOXQYCFHDMMGV-UHFFFAOYSA-N

InChi :
InChI=1S/C14H32N2O4/c1-11(17)7-15(8-12(2)18)5-6-16(9-13(3)19)10-14(4)20/h11-14,17-20H,5-10H2,1-4H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Quadrol is an immunostimulant and has been implicated as a potentially useful agent in accelerated wound healing.|Product information|CAS Number: 102-60-3|Molecular Weight: 292.41|Formula: C14H32N2O4|Chemical Name: 1-({2-[bis(2-hydroxypropyl)amino]ethyl}(2-hydroxypropyl)amino)propan-2-ol|Smiles: CC(O)CN(CC(C)O)CCN(CC(C)O)CC(C)O|InChiKey: NSOXQYCFHDMMGV-UHFFFAOYSA-N|InChi: InChI=1S/C14H32N2O4/c1-11(17)7-15(8-12(2)18)5-6-16(9-13(3)19)10-14(4)20/h11-14,17-20H,5-10H2,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (341.99 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Results show that viability of macrophages incubated with Quadrol at concentrations of 0.5 mM, 1 mM and 4mM are identical to that for controls.{{Tetrakis(triphenylphosphine)palladium} site|{Tetrakis(triphenylphosphine)palladium} {Biochemical Assay Reagents}|{Tetrakis(triphenylphosphine)palladium} Purity & Documentation|{Tetrakis(triphenylphosphine)palladium} Purity|{Tetrakis(triphenylphosphine)palladium} custom synthesis|{Tetrakis(triphenylphosphine)palladium} Autophagy} Viability, however, is reduced to 50% of control at concentrations of 16 mM to 32 mM.{{Cariprazine} MedChemExpress|{Cariprazine} GPCR/G Protein|{Cariprazine} Purity & Documentation|{Cariprazine} Description|{Cariprazine} custom synthesis|{Cariprazine} Epigenetic Reader Domain} After four hours, at concentrations of 1 mM and 4 mM, Quadrol produces enhanced spreading of 88% and 80%, respectively, as compared to the control of 28%.PMID:25147652 Quadrol, at a concentration of 16 mM, shows reduced percentage of spreading of macrophages after four hours. Exposure of macrophages to 1.0 mM or 4.0 mM Quadrol concentrations enhances phagocytic activity, 41% and 57%, respectively, over that of the cells exposed to media alone (34%).|In Vivo:|On day eight after the implantation, the amount of collagen in the implants of normal mice injected with Quadrol exceeds controls by more than 200% (pProducts are for research use only. Not for human use.|

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