Product Name :
Glyburide-d3
CAS No.:
1219803-02-7
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Please store the product under the recommended conditions in the Certificate of Analysis.
SMILES:
Product Description :
Glyburide-d3 (Glyburide-d3) is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability.{{2055200-88-7} site|{2055200-88-7} Technical Information|{2055200-88-7} Formula|{2055200-88-7} manufacturer} Glibenclamide can induce autophagy.
Formula:
C23H25D3ClN3O5S
Molecular Weight :
497.02
Synonyms:
Glyburide-d3
Additional Information:
|CAS No. 1219803-02-7 ; |Synonyms Glyburide-d3 ; |Formula C23H25D3ClN3O5S ; |Molecular Weight 497.02 ; |Product Description Glyburide-d3 (Glyburide-d3) is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity.{{11061-68-0} MedChemExpress|{11061-68-0} Biological Activity|{11061-68-0} Description|{11061-68-0} manufacturer} Glibenclamide inhibits P-glycoprotein.PMID:28613755 Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Please store the product under the recommended conditions in the Certificate of Analysis.