Product Name :
Anti-SNCA, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-SNCA, Human antibody is designed for detecting human SNCA specifically. Based on ELISA and/or FCM, Anti-SNCA, Human antibody reacts with human SNCA specifically. | Immunogen: Recombinant human SNCA | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human SNCA | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking. Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways. Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson’s disease. Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer’s disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene. Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.
Description2 :
Anti-SNCA, Human antibody is designed for detecting human SNCA specifically.{{1221186-53-3} web|{1221186-53-3} Technical Information|{1221186-53-3} Description|{1221186-53-3} manufacturer} Based on ELISA and/or FCM, Anti-SNCA, Human antibody reacts with human SNCA specifically.{{1323403-33-3} MedChemExpress|{1323403-33-3} Purity & Documentation|{1323403-33-3} Formula|{1323403-33-3} supplier}
Immunogen:
Recombinant human SNCA
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc.PMID:31082056 The actual dilution used must be determined empirically.