Taken with each other, expression profiling confirms a huge overlap in gene regulation amongst psoriasis and the skin ailment in PPARb/d mice, strongly suggesting that the phenotype similarities described earlier mentioned are not a phenocopy but involve overlapping signalling pathways
Skin phenotype in PPARb/d TG mice twenty days after GW501516 (GW) administration for twenty days. (a) Gross morphology, (d) H&E histology of management mice not handled with GW (d), or…