That minute ventilation was equivalent suggests the inhaled load of nicotine is equivalent in both equally smoke alone and smoke+menthol exposed mice. Cotinine is the key metabolite of nicotine [37]
It has been unidentified regardless of whether these mechanisms are also delicate to inhibition by L-menthol. The counterirritant results of L-menthol are probably owing to stimulation of the TRPM8 receptor.…