The perinuclear staining of AP-three was minimized in cells co-transfected with rabip4′ and rab4 or rab4Q67L, similar to one rab4 and rab4Q67L transfectants
Considering that lysosomes in management cells had been current alongside microtubule tracks, this instructed possibly an accelerated anterograde transport or a deficiency in retrograde, dynein-mediated transportation. Dynein recruitment to lysosomes…